Your Location：Home >Produts >API >1201902-80-8
Product Details
Manufacturers supply cost-effective and customizable MLN9708 1201902-80-8 We supply high quality MLN9708 (CAS 1201902-80-8), in stock, factory directly supply to clients, lower prices, more competitiveness.
MLN9708 is , while it's Molecular Formula is C20H23BCl2N2O9. MLN-9708 is a novel proteasome?inhibitor.
The CAS number of MLN9708 is 1201902-80-8.
More information of MLN9708 1201902-80-8 are:
|
Synonyms |
4-Carboxy-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-acetic acid; Ixazomib |
|
CAS Number |
1201902-80-8 |
|
Molecular Formula |
C20H23BCl2N2O9 |
|
Molecular Weight |
517.128 |
|
Density |
1.47 |
|
HS CODE |
29329990 |
|
PSA |
168.33000 |
|
LogP |
2.74480 |
|
Pka |
1.92±0.20(Predicted) |
Ixazomib citrate is a proteasome inhibitor prodrug for the treatment of multiple myeloma in patients who have received at least one prior therapy in combination with lenalidomide and dexamethasone. The drug was developed by Takeda and reversibly inhibits the protein proteasome subunit β type-5, which is part of the 20S proteasome complex. Ixazomib citrate (XXIV) is hydrolyzed quickly in vivo to give the biologically active compound ixazomib, which presumably is the corresponding boronic acid variant of XXIV.
Articles related to MLN9708:
|
Article |
Source |
|
Synthetic process research of ixazomib |
- Paragraph 0004; 0012, (2019/11/04) |
|
BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF |
- Page/Page column 63, (2010/01/12) |
Luhan Pharmachem Co., Ltd. is a quality supplier and manufacturer of MLN9708 . You can buy high quality, low price MLN9708 1201902-80-8 here. Contact us.
Tel:+86 0871 6511 0906Phone:188 1221 6310
