What is the (+)-Bis[(R)-1-phenylethyl]amine?

(+)-Bis[(R)-1-phenylethyl]amine is , while it's Molecular Formula is C 16 H 19 N. (+)-Bis[(R)-1-phenylethyl]amine can be used:In the synthesis of?β-amino acids.In the preparation of chiral C(19)-C(26) and C(27)-C(32) moieties of scytophycin C.To induce enantioselectivity in the deprotonation of prochiral ketones.As a starting material for the synthesis of chiral phenolate ligands through Mannich condensation reaction.In the synthesis of chiral phosphoramidite ligands.To prepare chiral cyclic isoimidium salts, which are further used to synthesize chiral lactones through Diels-Alder reaction.

What is the CAS number for (+)-Bis[(R)-1-phenylethyl]amine?

The CAS number of (+)-Bis[(R)-1-phenylethyl]amine is 23294-41-9.

What is (+)-Bis[(R)-1-phenylethyl]amine (23294-41-9) used for?

(+)-Bis[(R)-1-phenylethyl]amine is an organic compound that plays a significant role in the creation of chirally optically active drugs and compounds. It is characterized by its unique structure, which allows it to be used as an intermediate in various chemical reactions. (+)-Bis[(R)-1-phenylethyl]amine is essential in the pharmaceutical industry due to its ability to induce enantioselectivity and contribute to the synthesis of complex molecules with specific stereochemistry.InChI:InChI=1/C16H19N/c1-13(15-9-5-3-6-10-15)17-14(2)16-11-7-4-8-12-16/h3-14,17H,1-2H3/t13-,14-/m1/s1

What is the (+)-Bis[(R)-1-phenylethyl]amine?

(+)-Bis[(R)-1-phenylethyl]amine is , while it's Molecular Formula is C 16 H 19 N. (+)-Bis[(R)-1-phenylethyl]amine can be used:In the synthesis of?β-amino acids.In the preparation of chiral C(19)-C(26) and C(27)-C(32) moieties of scytophycin C.To induce enantioselectivity in the deprotonation of prochiral ketones.As a starting material for the synthesis of chiral phenolate ligands through Mannich condensation reaction.In the synthesis of chiral phosphoramidite ligands.To prepare chiral cyclic isoimidium salts, which are further used to synthesize chiral lactones through Diels-Alder reaction.

What is the CAS number for (+)-Bis[(R)-1-phenylethyl]amine?

The CAS number of (+)-Bis[(R)-1-phenylethyl]amine is 23294-41-9.

What is (+)-Bis[(R)-1-phenylethyl]amine (23294-41-9) used for?

(+)-Bis[(R)-1-phenylethyl]amine is an organic compound that plays a significant role in the creation of chirally optically active drugs and compounds. It is characterized by its unique structure, which allows it to be used as an intermediate in various chemical reactions. (+)-Bis[(R)-1-phenylethyl]amine is essential in the pharmaceutical industry due to its ability to induce enantioselectivity and contribute to the synthesis of complex molecules with specific stereochemistry.InChI:InChI=1/C16H19N/c1-13(15-9-5-3-6-10-15)17-14(2)16-11-7-4-8-12-16/h3-14,17H,1-2H3/t13-,14-/m1/s1

23294-41-9

Product Name(+)-Bis[(R)-1-phenylethyl]amine
Molecular FormulaC₁₆H₁₉N
Molecular Weight225.334
Purity99%

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CasNo： 23294-41-9
Molecular Formula： C₁₆H₁₉N
Purity： 99%

Buy cost-effective 99% pure (+)-Bis[(R)-1-phenylethyl]amine 23294-41-9 now

Molecular Formula:C₁₆H₁₉N
Molecular Weight:225.334
Vapor Pressure:0.00143mmHg at 25°C
Melting Point:~260 °C
Refractive Index:n20/D 1.5523(lit.)
Boiling Point:296.5 °C at 760 mmHg
PKA:8.79±0.29(Predicted)
Flash Point:137.2 °C
PSA：12.03000
Density:0.995 g/cm³
LogP:4.48930

(+)-Bis[(R)-1-phenylethyl]amine(Cas 23294-41-9) Usage

InChI:InChI=1/C16H19N/c1-13(15-9-5-3-6-10-15)17-14(2)16-11-7-4-8-12-16/h3-14,17H,1-2H3/t13-,14-/m1/s1

23294-41-9 Relevant articles

An Iridium Catalytic System Compatible with Inorganic and Organic Nitrogen Sources for Dual Asymmetric Reductive Amination Reactions

Chang, Mingxin,Gao, Zhaofeng,Geng, Huiling,Huang, Haizhou,Liu, Jingwen

supporting information, p. 27307 - 27311 (2021/11/17)

Asymmetric reductive amination (ARA) is ...

Method for synthesizing chiral phosphite ligand based on R - 2 - phenylethylamine

-

, (2021/10/27)

The invention discloses a method for syn...

One-Pot Synthesis of Symmetrical Tertiary and Secondary Amines from Carbonyl Compounds, Ammonium Carbonate and Carbon Monoxide as a Reductant

Muratov, Karim,Afanasyev, Oleg I.,Kuchuk, Ekaterina,Runikhina, Sofiya,Chusov, Denis

supporting information, p. 6557 - 6560 (2019/10/22)

Rh-catalyzed one-step synthesis of terti...

B(C6F5)3-Catalyzed Asymmetric Reductive Amination of Ketones with Ammonia Borane

Pan, Zhentao,Shen, Leixin,Song, Dingguo,Xie, Zhen,Ling, Fei,Zhong, Weihui

, p. 11502 - 11509 (2018/09/25)

The first example of metal-free B(C6F5)3...

23294-41-9 Process route

: 2627-86-3
(S)-1-phenyl-ethylamine

: 98-86-2
acetophenone

: 98-85-1,13323-81-4
1-Phenylethanol

: 21003-56-5,21003-57-6,23294-41-9,42287-48-9,56210-72-1,10024-74-5
(1S,1'S)-bis(1-phenylethyl)amine

Conditions

Conditions	Yield
(S)-1-phenyl-ethylamine; acetophenone; With tris(pentafluorophenyl)borate; In toluene; at 60 ℃; for 8h; With ammonia borane; In toluene; at 60 ℃; for 4h; Solvent; Temperature; diastereoselective reaction;	37% 53%

: 98-86-2
acetophenone

: 2627-86-3
(S)-1-phenyl-ethylamine

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 21003-56-5,21003-57-6,23294-41-9,42287-48-9,56210-72-1,10024-74-5
(1S,1'S)-bis(1-phenylethyl)amine

: 10024-74-5,21003-56-5,21003-57-6,23294-41-9,42287-48-9,56210-72-1
(R,R)-N,N-bis-(1-phenylethyl)amine

: 21003-57-6,1163726-07-5
(R,S)-bis(1-phenylethyl)amine

Conditions

Conditions	Yield
With bis(1,5-cyclooctadiene)diiridium(I) dichloride; (R)-1-[(S_P)-2-(diphenylphosphino)ferrocenyl]ethyl-di-tert-butylphosphine; ammonium acetate; hydrogen; toluene-4-sulfonic acid; In methanol; dichloromethane; at 80 ℃; for 24h; under 45603.1 Torr; stereoselective reaction; Autoclave;	4 % ee 12 % ee
With bis(1,5-cyclooctadiene)diiridium(I) dichloride; C₃₇H₃₀NO₂P; ammonium acetate; hydrogen; toluene-4-sulfonic acid; In methanol; dichloromethane; at 80 ℃; for 24h; under 45603.1 Torr; Reagent/catalyst; stereoselective reaction; Autoclave;	26 % ee 6 % ee
With bis(1,5-cyclooctadiene)diiridium(I) dichloride; ammonium acetate; hydrogen; C₄₅H₃₄NO₂P; toluene-4-sulfonic acid; In methanol; dichloromethane; at 80 ℃; for 24h; under 45603.1 Torr; Reagent/catalyst; stereoselective reaction; Autoclave;	66 % ee 18 % ee

23294-41-9 Upstream products

40636-57-5
(αS)-α-methyl-N-(1-phenylethylidene)benzenemethanamine
2408-37-9
2,2,6-trimethylcyclohexan-1-one
25102-87-8
N-(α-methyl)benzylidene 1-phenylethanamine
2627-86-3
(S)-1-phenyl-ethylamine

23294-41-9 Downstream products

134431-04-2
tert-butyl (3R,αR,α'R)-3-(N,N-bis(α-methylbenzyl)amino)butanoate
134431-03-1
benzyl (3R,αR,α'R)-3-(N,N-bis(α-methylbenzyl)amino)butanoate
364782-99-0
N,N-bis[(1R)-1-phenylethyl]prop-2-enamide
376355-58-7
N,N-bis-[(S)-1-phenylethyl]dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine

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