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59-05-2

  • Product NameMethotrexate
  • Molecular FormulaC20H22N8O5
  • Molecular Weight454.445
  • Purity99%
  • Appearanceyellow crystalline powder
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  • CasNo: 59-05-2
  • Molecular Formula: C20H22N8O5
  • Appearance: yellow crystalline powder
  • Purity: 99%

Good factory supply good Methotrexate 59-05-2 We provide high quality Methotrexate (CAS 59-05-2), at a very affordable prices to our customers.

1.What is the Methotrexate ?

Methotrexate is an antineoplastic and antirheumatic drug that acts as a folic acid antagonist. It is a deuterated form of folic acid, which allows it to cross the blood-brain barrier and exhibit potential anxiolytic and vasodilator activities.

Methotrexate, for example, is highly bound to serum albumin and can be displaced by salicylates, sulfonamides, phenothiazines, phenytoin, and other organic acids. The induction of hepatic drugmetabolizing enzymes by phenobarbital may alter the metabolism of cyclophosphamide to both active and inactive metabolites. Mercaptopurine metabolism is blocked by allopurinol, an occurrence that may result in lethal toxicity if the dosage of mercaptopurine is not reduced to one-fourth of the usual dosage. Methotrexate is secreted actively by the renal tubules, and its renal clearance may be delayed by salicylates.

Used as a antineoplastic and antirheumatic. A folic Acid antagonist

2.What is the CAS number for Methotrexate ?

The CAS number of Methotrexate is 59-05-2.

More information of Methotrexate 59-05-2 are:

CAS Number

59-05-2

Density

1.536 g/cm3

Melting Point

195 °C

Boiling Point

561.26°C (rough estimate)

Flash Point

11℃

Refractive Index

1.6910 (estimate)

HS CODE

29335995

PSA

210.54000

LogP

1.82170

Pka

pKa 3.04/4.99(H2O,t =25,I=0.0025) (Uncertain)

3.What is the molecular formula of Methotrexate ?

The chemical formula of Methotrexate is C20H22N8O5 which containing 20 Carbon atoms,22 Hydrogen atoms,8 Nitrogen atoms and 5 Oxygen atoms,and the molecular weight, and the molecular weight of Methotrexate is 454.445

4.What is Methotrexate(59-05-2)used for?

Methotrexate is an antineoplastic and antirheumatic drug that acts as a folic acid antagonist. It is a deuterated form of folic acid, which allows it to cross the blood-brain barrier and exhibit potential anxiolytic and vasodilator activities.

InChI:InChI=1/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m1/s1

Relevant articles related to Methotrexate:

Article

Source

METHOTREXATE ANALOGS AND METHODS OF USE

-

, (2022/01/04)

5.Good factory supply good Methotrexate 59-05-2

Luhan Pharmachem Co., Ltd. is a quality supplier of Methotrexate. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Methotrexate 59-05-2.

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